Life is found in remote and extreme places on earth – from the Dead Sea to hot springs and acidic swamps. Proteins, a key part of every life form, have adapted to function in these extreme conditions. Yet, proteins that live along the equator paradise don’t need such adaptation. Amai applies AI-CPD to adapt the proteins found in nature to be compatible with the extreme conditions found in food and beverages. These include high production yield, and improved stability (temperature, pH, non-aqueous milieu) and functionality.
Every protein is composed of a necklace (sequence) of twenty types of beads called amino acids. Computational Protein Design (CPD) is a method in which the protein amino acid necklace is examined and designed so as to naturally produce a new necklace of amino acids that is highly similar to the original protein yet confers beneficial properties such as taste, thermal-stability, acid-stability, shelf-life, expression yield and alike. The designer protein is 100% protein with a novel sequence of amino-acids. For more on CPD see the CPD book , edited by Ilan Samish, the founder and CEO of Amai Proteins.
Amai applies Agile-Integrative CPD (AI-CPD). In this platform the CPD is focused and guided according to the industrial implementation – food science, sensory analysis and regulatory aspects. The protein sequence is fit to the regulatory-approved host organism and to the specific sensory requirements of the protein within the expected food milieu.
AI-CPD, Agile Integrative Computational Protein Design
Since the dawn of mankind food has been produced with the help of yeast and other microorganisms. Examples include wine, beer, cheese and bread. Today, many ingredients are produced by regulatory-approved yeast. Just like one brews beer Amai Proteins produces non-GMO proteins for everyday use in foods and beverages.
Production by fermentation